Phosphorylation of LKB1/Par-4 Establishes Schwann Cell Polarity to Initiate and Control Myelin Extent

The Schwann cell (SC)-axon interface represents a membrane specialization that integrates axonal signals to coordinate cytoskeletal dynamics resulting in myelination. Here we show that LKB1/Par-4 is asymmetrically localized to the SC-axon interface and colocalizes with the polarity protein Par-3. Us...

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發表在:Nat Commun
Main Authors: Shen, Yun-An A., Chen, Yan, Dao, Dang Q., Mayoral, Sonia R., Wu, Laiman, Meijer, Dies, Ullian, Erik M., Chan, Jonah R., Lu, Q. Richard
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334370/
https://ncbi.nlm.nih.gov/pubmed/25255972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5991
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