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Targeted lung cancer therapy: preparation and optimization of transferrin-decorated nanostructured lipid carriers as novel nanomedicine for co-delivery of anticancer drugs and DNA

PURPOSE: Nanostructured lipid carriers (NLC) represent an improved generation of lipid nanoparticles. They have specific nanostructures to accommodate drugs/genes, and thus achieve higher loading capacity. The aim of this study was to develop transferrin (Tf)-decorated NLC as multifunctional nanomed...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Shao, Zhenyu, Shao, Jingyu, Tan, Bingxu, Guan, Shanghui, Liu, Zhulong, Zhao, Zengjun, He, Fangfang, Zhao, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334334/
https://ncbi.nlm.nih.gov/pubmed/25709444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S77837
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