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Chromosomal Abnormalities in Spleens of New Zealand Black Mice, A Strain Characterized by Autoimmunity and Malignancy

Mosaicism of normal and chromosomally aberrant cells was detected in 14 of 20 spleens from adult New Zealand Black (NZB) mice reared under conventional conditions, a strain that spontaneously develops autoimmunity and lymphoreticular malignancy. No abnormalities were found in marrows from these same...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Fialkow, Philip J., Paton, Gillian R., East, June
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1973
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433433/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4515606/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.4.1094
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