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Activation of Prolyl Hydroxylase in L-929 Fibroblasts by Ascorbic Acid

The addition of ascorbate to the culture medium of early log-phase mouse fibroblasts (L-929 cells) resulted in a 5-fold increase of prolyl hydroxylase activity. Maximal activity was reached within 2 hr after addition of 5 μM ascorbate. The total amount of enzyme-related antigen did not change on tre...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Stassen, Frans L. H., Cardinale, George J., Udenfriend, Sidney
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1973
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433432/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4352224/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.4.1090
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