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Small molecule probes to target the human Mediator complex

The human Mediator complex is a central integrator for transcription and represents a primary interface that allows DNA-binding transcription factors to communicate their regulatory signals to the RNA polymerase II enzyme. Because Mediator is dynamic both in terms of subunit composition and structur...

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Bibliografische gegevens
Gepubliceerd in:Isr J Chem
Hoofdauteurs: Phillips, Andrew J., Taatjes, Dylan J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334163/
https://ncbi.nlm.nih.gov/pubmed/25705053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijch.201300039
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