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Ether-à-go-go family voltage-gated K(+) channels evolved in an ancestral metazoan and functionally diversified in a cnidarian–bilaterian ancestor

We examined the evolutionary origins of the ether-à-go-go (EAG) family of voltage-gated K(+) channels, which have a strong influence on the excitability of neurons. The bilaterian EAG family comprises three gene subfamilies (Eag, Erg and Elk) distinguished by sequence conservation and functional pro...

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Détails bibliographiques
Publié dans:J Exp Biol
Auteurs principaux: Li, Xiaofan, Martinson, Alexandra S., Layden, Michael J., Diatta, Fortunay H., Sberna, Anna P., Simmons, David K., Martindale, Mark Q., Jegla, Timothy J.
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334144/
https://ncbi.nlm.nih.gov/pubmed/25696816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jeb.110080
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