Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer

The Bcl proteins play a critical role in apoptosis, as mutations in family members interfere with normal programmed cell death. Such events can cause cell transformation, potentially leading to cancer. Recent discoveries indicate that some viral proteins interfere with Bcl proteins either directly o...

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Detalhes bibliográficos
Publicado no:Infect Agent Cancer
Main Authors: Alibek, Kenneth, Irving, Stephanie, Sautbayeva, Zarina, Kakpenova, Ainur, Bekmurzayeva, Aliya, Baiken, Yeldar, Imangali, Nurgul, Shaimerdenova, Madina, Mektepbayeva, Damel, Balabiyev, Arnat, Chinybayeva, Aizada
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333878/
https://ncbi.nlm.nih.gov/pubmed/25699089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-9378-9-44
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