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Inactive Enzyme Molecules in Aging Mice: Liver Aldolase

Evidence is presented that there is a considerable accumulation of inactive fructose-1,6-diphosphate aldolase (EC 4.1.2.7) in the liver of senescent mice. Liver aldolase was purified from 3-month-old mice and used to immunize rabbits. It was demonstrated with the monospecific antibody thus produced...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gershon, Harriet, Gershon, David
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1973
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433386/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4197629/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.3.909
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