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Detection and Isolation of an Endoperoxide Intermediate in Prostaglandin Biosynthesis

An earlier proposed endoperoxide intermediate in the biosynthesis of prostaglandins was detected in short-time incubations of arachidonic acid with the microsomal fraction of homogenates of sheep vesicular glands. Conversion of the endoperoxide into prostaglandin E(2) was stimulated by reduced gluta...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Hamberg, Mats, Samuelsson, Bengt
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1973
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433384/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4514999/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.3.899
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