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Detection of Protein–Small Molecule Binding Using a Self-Referencing External Cavity Laser Biosensor
[Image: see text] High-throughput screening has enabled the identification of small molecule modulators of important drug targets via well-established colorimetric or fluorimetric activity assays. However, existing methods to identify small molecule binders of nonenzymatic protein targets lack eithe...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333586/ https://ncbi.nlm.nih.gov/pubmed/24720510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500636p |
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