Temporal Analysis of Genome Alterations Induced by Single-Cell Passaging in Human Embryonic Stem Cells

Simplified culture conditions are essential for large-scale drug screening and medical applications of human pluripotent stem cells (hPSCs). However, hPSCs [ie, human embryonic stem cells (hESCs), and human induced pluripotent stem cells (iPSCs) are prone to genomic instability, a phenomenon that is...

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Publicat a:Stem Cells Dev
Autors principals: Bai, Qiang, Ramirez, Jean-Marie, Becker, Fabienne, Pantesco, Véronique, Lavabre-Bertrand, Thierry, Hovatta, Outi, Lemaître, Jean-Marc, Pellestor, Franck, De Vos, John
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2015
Matèries:
Original Research Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333508/
https://ncbi.nlm.nih.gov/pubmed/25254421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2014.0292
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