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ACTN4 copy number increase as a predictive biomarker for chemoradiotherapy of locally advanced pancreatic cancer

BACKGROUND: Several clinical trials have compared chemotherapy alone and chemoradiotherapy (CRT) for locally advanced pancreatic cancer (LAPC) treatment. However, predictive biomarkers for optimal therapy of LAPC remain to be identified. We retrospectively estimated amplification of the ACTN4 gene t...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Watanabe, T, Ueno, H, Watabe, Y, Hiraoka, N, Morizane, C, Itami, J, Okusaka, T, Miura, N, Kakizaki, T, Kakuya, T, Kamita, M, Tsuchida, A, Nagakawa, Y, Wilber, H, Yamada, T, Honda, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333489/
https://ncbi.nlm.nih.gov/pubmed/25602965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.623
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