Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities

Host-adapted Gram-negative bacterial pathogens from the Pasteurellaceae, Neisseriaceae, and Moraxellaceae families normally reside in the upper respiratory or genitourinary tracts of their hosts and rely on utilizing iron from host transferrin (Tf) for growth and survival. The surface receptor prote...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Frandoloso, Rafael, Martínez-Martínez, Sonia, Calmettes, Charles, Fegan, Jamie, Costa, Estela, Curran, Dave, Yu, Rong-hua, Gutiérrez-Martín, César B., Rodríguez-Ferri, Elías F., Moraes, Trevor F., Schryvers, Anthony B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333475/
https://ncbi.nlm.nih.gov/pubmed/25547790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02572-14
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