Protective and Pathological Functions of CD8(+) T Cells in Leishmania braziliensis Infection

Cutaneous leishmaniasis (CL) caused by Leishmania braziliensis is characterized by a strong Th1 response that leads to skin lesion development. In areas where L. braziliensis transmission is endemic, up to 15% of healthy subjects have tested positive for delayed-type hypersensitivity to soluble leis...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Cardoso, Thiago Marconi, Machado, Álvaro, Costa, Diego Luiz, Carvalho, Lucas P., Queiroz, Adriano, Machado, Paulo, Scott, Phillip, Carvalho, Edgar M., Bacellar, Olívia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333467/
https://ncbi.nlm.nih.gov/pubmed/25534940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02404-14
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