Divergent Targets of Aspergillus fumigatus AcuK and AcuM Transcription Factors during Growth In Vitro versus Invasive Disease

In Aspergillus nidulans, the AcuK and AcuM transcription factors form a complex that regulates gluconeogenesis. In Aspergillus fumigatus, AcuM governs gluconeogenesis and iron acquisition in vitro and virulence in immunosuppressed mice. However, the function of AcuK was previously unknown. Through i...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Infect Immun
Main Authors: Pongpom, Monsicha, Liu, Hong, Xu, Wenjie, Snarr, Brendan D., Sheppard, Donald C., Mitchell, Aaron P., Filler, Scott G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Fungal and Parasitic Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333448/
https://ncbi.nlm.nih.gov/pubmed/25534941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02685-14
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