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A New Complement-Mediated Cytolytic Mechanism—the C1-Bypass Activation Pathway

A new cytolytic pathway is described whereby cells sensitized with cytotoxic antibody can be specifically lysed in the complete absence of intact, classical complement pathway function. Evaluation of this model with sera deficient in the 4th (C4), 2nd (C2), and 6th (C6) components of complement has...

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Bibliographic Details
Main Authors: May, Joseph E., Frank, Michael M.
Format: Artigo
Language:Inglês
Published: 1973
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC433326/
https://ncbi.nlm.nih.gov/pubmed/4123687
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