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Anti-Sclerostin Antibody Treatment in a Rat Model of Progressive Renal Osteodystrophy

Chronic Kidney Disease (CKD) is associated with abnormalities in bone quantity and quality leading to increased fractures. Recent studies suggest abnormalities of Wnt signaling in animal models of CKD and elevated sclerostin levels in patients with CKD. The goal of this study was to evaluate the eff...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Moe, Sharon M., Chen, Neal X., Newman, Christopher L., Organ, Jason M., Kneissel, Michaela, Kramer, Ina, Gattone, Vincent H., Allen, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333005/
https://ncbi.nlm.nih.gov/pubmed/25407607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2372
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