Hydroxyphenylazopyrimidines: Characterization of the Active Forms and Their Inhibitory Action on a DNA Polymerase from Bacillus subtilis

The active forms of 6-(p-hydroxyphenylazo)-uracil and 6-(p-hydroxyphenylazo)-isocytosine were isolated and identified as their respective hydrazino derivatives. These arylhydrazino pyrimidines selectively inhibited a chromatographically distinct DNA polymerase from Bacillus subtilis. The actions of...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Mackenzie, John M., Neville, Marilyn M., Wright, George E., Brown, Neal C.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1973
Sujets:	Biological Sciences: Biochemistry
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4631357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.2.512
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