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Curing a viral infection by targeting the host: The example of cyclophilin inhibitors

Every step of the viral life cycle is dependent on the host, which potentially can be explored for antiviral targets. Historically, however, drug discovery has focused mainly on viral targets, because of their perceived specificity. Efforts to pursue host targets have been largely hampered by concer...

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Bibliografske podrobnosti
izdano v:Antiviral Res
Main Authors: Lin, Kai, Gallay, Philippe
Format: Artigo
Jezik:Inglês
Izdano: Elsevier B.V. 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332838/
https://ncbi.nlm.nih.gov/pubmed/23578729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.03.020
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