Potassium Modulates Electrolyte Balance and Blood Pressure through Effects on Distal Cell Voltage and Chloride

Dietary potassium deficiency, common in Western diets, raises blood pressure and enhances salt sensitivity. Potassium homeostasis requires a molecular switch in the distal convoluted tubule (DCT), which fails in familial hyperkalemic hypertension (pseudohypoaldosteronism type 2), activating the thia...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Terker, Andrew S., Zhang, Chong, McCormick, James A., Lazelle, Rebecca A., Zhang, Chengbiao, Meermeier, Nicholas P., Siler, Dominic A., Park, Hae J., Fu, Yi, Cohen, David M., Weinstein, Alan M., Wang, Wen-Hui, Yang, Chao-Ling, Ellison, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332769/
https://ncbi.nlm.nih.gov/pubmed/25565204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.12.006
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