Hyper-IL-15 suppresses metastatic and autochthonous liver cancer by promoting tumour-specific CD8(+) T cell responses

BACKGROUND & AIMS: Liver cancer has a very dismal prognosis due to lack of effective therapy. Here, we studied the therapeutic effects of hyper-interleukin15 (hyper-IL-15), which is composed of IL-15 and the sushi domain of the IL-15 receptor α chain, on metastatic and autochthonous liver cancer...

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Pubblicato in:J Hepatol
Autori principali: Cheng, Liang, Du, Xuexiang, Wang, Zheng, Ju, Jianqi, Jia, Mingming, Huang, Qibin, Xing, Qiao, Xu, Meng, Tan, Yi, Liu, Mingyue, Du, Peishuang, Su, Lishan, Wang, Shengdian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332697/
https://ncbi.nlm.nih.gov/pubmed/25016226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2014.07.004
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