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Identification of small molecule inhibitors of cisplatin-induced hair cell death: Results of a 10,000 compound screen in the zebrafish lateral line
HYPOTHESIS: The zebrafish lateral line can be used to identify small molecules that protect against cisplatin-induced hair cell death. BACKGROUND: Cisplatin is a commonly used chemotherapeutic which causes hearing loss by damaging hair cells of the inner ear. There are currently no FDA-approved phar...
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| Publicado no: | Otol Neurotol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332566/ https://ncbi.nlm.nih.gov/pubmed/25687728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0000000000000487 |
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