Urinary prostasin excretion is associated with adiposity in non-hypertensive African American adolescents

BACKGROUND: Metabolic abnormalities in obesity can overstimulate the renal epithelial sodium channel (ENaC) and subsequently lead to blood pressure (BP) elevation. Prostasin, a membrane-bound/secretive serine protease, is thought to activate ENaC via the proteolytic cleavage of the channel. Our spec...

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發表在:Pediatr Res
Main Authors: Guo, De-huang, Parikh, Samip J., Chao, Julie, Pollock, Norman K., Wang, Xiaoling, Snieder, Harold, Navis, Gerjan, Wilson, James G., Bhagatwala, Jigar, Zhu, Haidong, Dong, Yanbin
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332551/
https://ncbi.nlm.nih.gov/pubmed/23863785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2013.81
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