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Urinary prostasin excretion is associated with adiposity in non-hypertensive African American adolescents
BACKGROUND: Metabolic abnormalities in obesity can overstimulate the renal epithelial sodium channel (ENaC) and subsequently lead to blood pressure (BP) elevation. Prostasin, a membrane-bound/secretive serine protease, is thought to activate ENaC via the proteolytic cleavage of the channel. Our spec...
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| Publicado no: | Pediatr Res |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332551/ https://ncbi.nlm.nih.gov/pubmed/23863785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2013.81 |
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