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Using the zebrafish lateral line to uncover novel mechanisms of action and prevention in drug-induced hair cell death

The majority of hearing loss and balance disorders are caused by the permanent loss of mechanosensory hair cells of the inner ear. Identification of genes and compounds that modulate susceptibility to hair cell death is frequently confounded by the difficulties of assaying for such complex phenomena...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Stawicki, Tamara M., Esterberg, Robert, Hailey, Dale W., Raible, David W., Rubel, Edwin W
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332341/
https://ncbi.nlm.nih.gov/pubmed/25741241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00046
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