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Ribosome binding of DNA analogs of tRNA requires base modifications and supports the "extended anticodon".

The efficiency of translation depends on correct tRNA-ribosome interactions. The ability of chemically synthesized yeast tRNA(Phe) anticodon domains to effectively inhibit the binding of native yeast tRNA(Phe) to poly(U)-programmed Escherichia coli 30S ribosomal subunits was dependent on a Mg(2+)-st...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Dao, V, Guenther, R, Malkiewicz, A, Nawrot, B, Sochacka, E, Kraszewski, A, Jankowska, J, Everett, K, Agris, P F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43322/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7510886/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.6.2125
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