Inhibition of RNA-Dependent DNA Polymerase of Rous Sarcoma Virus by Thiosemicarbazones and Several Cations

The RNA-dependent DNA polymerase of Rous sarcoma virus is inhibited by N-methyl isatin β-thiosemicarbazone and by thiosemicarbazide, but not by semicarbazide. These inhibitors also inactivate, upon contact with the virion, the transforming ability of Rous sarcoma virus. Sulfhydryl donors, such as 2-...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Levinson, Warren, Faras, Anthony, Woodson, Bruce, Jackson, Jean, Bishop, J. Michael
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1973
Fag:	Biological Sciences: Microbiology
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433207/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4119222/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.1.164
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