Hormone replacement therapy enhances IGF-1 signaling in skeletal muscle by diminishing miR-182 and miR-223 expressions: a study on postmenopausal monozygotic twin pairs

MiRNAs are fine-tuning modifiers of skeletal muscle regulation, but knowledge of their hormonal control is lacking. We used a co-twin case–control study design, that is, monozygotic postmenopausal twin pairs discordant for estrogen-based hormone replacement therapy (HRT) to explore estrogen-dependen...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Olivieri, Fabiola, Ahtiainen, Maarit, Lazzarini, Raffaella, Pöllänen, Eija, Capri, Miriam, Lorenzi, Maria, Fulgenzi, Gianluca, Albertini, Maria C, Salvioli, Stefano, Alen, Markku J, Kujala, Urho M, Borghetti, Giulia, Babini, Lucia, Kaprio, Jaakko, Sipilä, Sarianna, Franceschi, Claudio, Kovanen, Vuokko, Procopio, Antonio D
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331762/
https://ncbi.nlm.nih.gov/pubmed/25040542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12245
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