Phosphatidylinositol binding of Saccharomyces cerevisiae Pdr16p represents an essential feature of this lipid transfer protein to provide protection against azole antifungals

Pdr16p is considered a factor of clinical azole resistance in fungal pathogens. The most distinct phenotype of yeast cells lacking Pdr16p is their increased susceptibility to azole and morpholine antifungals. Pdr16p (also known as Sfh3p) of Saccharomyces cerevisiae belongs to the Sec14 family of pho...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Cell Biol Lipids
Main Authors: Holič, Roman, Šimová, Zuzana, Ashlin, Tim, Pevala, Vladimír, Poloncová, Katarína, Tahotná, Dana, Kutejová, Eva, Cockcroft, Shamshad, Griač, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331669/
https://ncbi.nlm.nih.gov/pubmed/25066473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2014.07.014
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