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Upregulation of cardioprotective SUR2A by sub-hypoxic drop in oxygen

The effects of hypoxia on gene expression have been vigorously studied, but possible effects of small changes in oxygen tension have never been addressed. SUR2A is an atypical ABC protein serving as a regulatory subunit of sarcolemmal ATP-sensitive K(+) (K(ATP)) channels. Up-regulation of SUR2A is a...

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Veröffentlicht in:Biochim Biophys Acta Mol Cell Res
Hauptverfasser: Mohammed Abdul, Khaja Shameem, Jovanović, Sofija, Sukhodub, Andriy, Du, Qingyou, Jovanović, Aleksandar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331663/
https://ncbi.nlm.nih.gov/pubmed/25064694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.07.007
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