Brain Amyloid-β Burden Is Associated with Disruption of Intrinsic Functional Connectivity within the Medial Temporal Lobe in Cognitively Normal Elderly

The medial temporal lobe is implicated as a key brain region involved in the pathogenesis of Alzheimer's disease (AD) and consequent memory loss. Tau tangle aggregation in this region may develop concurrently with cortical Aβ deposition in preclinical AD, but the pathological relationship betwe...

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Publicado no:J Neurosci
Main Authors: Song, Zhuang, Insel, Philip S., Buckley, Shannon, Yohannes, Seghel, Mezher, Adam, Simonson, Alix, Wilkins, Sarah, Tosun, Duygu, Mueller, Susanne, Kramer, Joel H., Miller, Bruce L., Weiner, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331637/
https://ncbi.nlm.nih.gov/pubmed/25698758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2092-14.2015
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