Efficacy, safety, pharmacokinetics and biomarker findings in patients with HER2-positive advanced or metastatic breast cancer treated with lapatinib in combination with capecitabine: results from 51 Japanese patients treated in a clinical study

BACKGROUND: The results from a phase III trial conducted outside of Japan demonstrated a significant improvement in time to progression (TTP) when lapatinib was combined with capecitabine compared with capecitabine alone in patients with HER2-positive advanced or metastatic breast cancer. In this cl...

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Detalhes bibliográficos
Publicado no:Breast Cancer
Main Authors: Iwata, Hiroji, Fujii, Hirofumi, Masuda, Norikazu, Mukai, Hirofumi, Nishimura, Yuichiro, Katsura, Koichi, Ellis, Catherine E., Gagnon, Robert C., Nakamura, Seigo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331616/
https://ncbi.nlm.nih.gov/pubmed/23689990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12282-013-0475-1
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