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Mechanism of action of penicillin: triggering of the pneumococcal autolytic enzyme by inhibitors of cell wall synthesis.

During penicillin treatment of an autolysin defective mutant pneumococcus we have observed three novel phenomena: (i) Growth of the mutant cultures is inhibited by the same concentrations of penicillin that induce lysis in the wild type. (ii) Mutant bacteria treated with the minimum growth inhibitor...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Tomasz, A, Waks, S
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1975
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433160/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/674/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.10.4162
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