Sildenafil Ameliorates Long Term Peripheral Neuropathy in Type II Diabetic Mice

Diabetic peripheral neuropathy is a common complication of long-standing diabetes mellitus. To mimic clinical trials in which patients with diabetes enrolled have advanced peripheral neuropathy, we investigated the effect of sildenafil, a specific inhibitor of phosphodiesterase type 5 enzyme, on lon...

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Publicat a:PLoS One
Autors principals: Wang, Lei, Chopp, Michael, Szalad, Alexandra, Jia, LongFei, Lu, XueRong, Lu, Mei, Zhang, Li, Zhang, Yi, Zhang, RuiLan, Zhang, Zheng Gang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331563/
https://ncbi.nlm.nih.gov/pubmed/25689401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118134
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