Pre-Transplant Donor-Specific T-Cell Alloreactivity Is Strongly Associated with Early Acute Cellular Rejection in Kidney Transplant Recipients Not Receiving T-Cell Depleting Induction Therapy

Preformed T-cell immune-sensitization should most likely impact allograft outcome during the initial period after kidney transplantation, since donor-specific memory T-cells may rapidly recognize alloantigens and activate the effector immune response, which leads to allograft rejection. However, the...

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Udgivet i:PLoS One
Main Authors: Crespo, Elena, Lucia, Marc, Cruzado, Josep M., Luque, Sergio, Melilli, Edoardo, Manonelles, Anna, Lloberas, Nuria, Torras, Joan, Grinyó, Josep M., Bestard, Oriol
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331510/
https://ncbi.nlm.nih.gov/pubmed/25689405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117618
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