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Classification of Beta-Lactamases and Penicillin Binding Proteins Using Ligand-Centric Network Models

β-lactamase mediated antibiotic resistance is an important health issue and the discovery of new β-lactam type antibiotics or β-lactamase inhibitors is an area of intense research. Today, there are about a thousand β-lactamases due to the evolutionary pressure exerted by these ligands. While β-lacta...

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Bibliographic Details
Published in:PLoS One
Main Authors: Öztürk, Hakime, Ozkirimli, Elif, Özgür, Arzucan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331424/
https://ncbi.nlm.nih.gov/pubmed/25689853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117874
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