Induction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemia.

Sister chromatid exchanges, which may reflect chromosome repair in response to certain types of DNA damage, provide a means of investigating the increased chromosome fragility characteristic of Fanconi's anemia. By a recently developed technique using 33258 Hoechst and 5-bromodeoxyuridine, it w...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Latt, S A, Stetten, G, Juergens, L A, Buchanan, G R, Gerald, P S
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1975
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433139/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1060089/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.10.4066
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