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Erythropoietin and organ protection: lessons from negative clinical trials

Based on its pleiotropic effects, erythropoietin can decrease inflammation, oxidative stress, and apoptosis. Erythropoietin provides organ protection for the heart, brain, and kidney in diverse preclinical animal studies, especially models that include ischemia–reperfusion injury and/or inflammation...

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Bibliographic Details
Published in:Crit Care
Main Author: Pearl, Ronald G
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331307/
https://ncbi.nlm.nih.gov/pubmed/25672222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0526-9
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