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Novobiocin and Peptide Analogs of α-factor are Positive Allosteric Modulators of the Yeast G Protein-Coupled Receptor Ste2p

G protein-coupled receptors (GPCRs) are the target of many drugs prescribed for human medicine and are therefore the subject of intense study. It has been recognized that compounds called allosteric modulators can regulate GPCR activity by binding to the receptor at sites distinct from, or overlappi...

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Détails bibliographiques
Publié dans:Biochim Biophys Acta
Auteurs principaux: Rymer, Jeffrey K., Hauser, Melinda, Bourdon, Allen K., Campagna, Shawn R., Naider, Fred, Becker, Jeffrey M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331264/
https://ncbi.nlm.nih.gov/pubmed/25576192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.12.024
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