Alpha-Lipoic Acid Activates eNOS through Activation of PI(3)-Kinase/Akt Signaling Pathway

BACKGROUND: Lipoic acid (LA) exerts therapeutic effects on cardiovascular diseases. However, the mechanisms underlying these therapeutic effects remain elusive. Endothelial nitric oxide synthase (eNOS) plays a critical role in cardiovascular homeostasis. LA was shown to potently activate PI3-kinase/...

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Vydáno v:Vascul Pharmacol
Hlavní autoři: Ying, Zhekang, Xie, Xiaoyun, Chen, Minjie, Yi, Kevin, Rajagopalan, Sanjay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331247/
https://ncbi.nlm.nih.gov/pubmed/25460366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2014.11.004
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