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Cladograms with Path to Event (ClaPTE): A novel algorithm to detect associations between genotypes or phenotypes using phylogenies

BACKGROUND: Associations between genotype and phenotype provide insight into the evolution of pathogenesis, drug resistance, and the spread of pathogens between hosts. However, common ancestry can lead to apparent associations between biologically unrelated features. The novel method Cladograms with...

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Detalhes bibliográficos
Publicado no:Comput Biol Med
Main Authors: Handelman, Samuel K, Aaronson, Jacob M., Seweryn, Michal, Voronkin, Igor, Kwiek, Jesse J., Sadee, Wolfgang, Verducci, Joseph S., Janies, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331246/
https://ncbi.nlm.nih.gov/pubmed/25577610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiomed.2014.12.013
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