Establishment of a Patient-Derived Orthotopic Xenograft (PDOX) Model of HER-2-Positive Cervical Cancer Expressing the Clinical Metastatic Pattern

Squamous cell carcinoma of the cervix, highly prevalent in the developing world, is often metastatic and treatment resistant with no standard treatment protocol. Our laboratory pioneered the patient-derived orthotopic xenograft (PDOX) nude mouse model with the technique of surgical orthotopic implan...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Hiroshima, Yukihiko, Zhang, Yong, Zhang, Nan, Maawy, Ali, Mii, Sumiyuki, Yamamoto, Mako, Uehara, Fuminari, Miwa, Shinji, Yano, Shuya, Murakami, Takashi, Momiyama, Masashi, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Murata, Takuya, Endo, Itaru, Hoffman, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331082/
https://ncbi.nlm.nih.gov/pubmed/25689852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117417
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