Commensal microbiota influence systemic autoimmune responses

Antinuclear antibodies are a hallmark feature of generalized autoimmune diseases, including systemic lupus erythematosus and systemic sclerosis. However, the processes underlying the loss of tolerance against nuclear self-constituents remain largely unresolved. Using mice deficient in lymphotoxin an...

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Published in:EMBO J
Main Authors: Van Praet, Jens T, Donovan, Erin, Vanassche, Inge, Drennan, Michael B, Windels, Fien, Dendooven, Amélie, Allais, Liesbeth, Cuvelier, Claude A, van de Loo, Fons, Norris, Paula S, Kruglov, Andrey A, Nedospasov, Sergei A, Rabot, Sylvie, Tito, Raul, Raes, Jeroen, Gaboriau-Routhiau, Valerie, Cerf-Bensussan, Nadine, Van de Wiele, Tom, Eberl, Gérard, Ware, Carl F, Elewaut, Dirk
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331001/
https://ncbi.nlm.nih.gov/pubmed/25599993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489966
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