Commensal microbiota influence systemic autoimmune responses

Antinuclear antibodies are a hallmark feature of generalized autoimmune diseases, including systemic lupus erythematosus and systemic sclerosis. However, the processes underlying the loss of tolerance against nuclear self-constituents remain largely unresolved. Using mice deficient in lymphotoxin an...

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發表在:EMBO J
Main Authors: Van Praet, Jens T, Donovan, Erin, Vanassche, Inge, Drennan, Michael B, Windels, Fien, Dendooven, Amélie, Allais, Liesbeth, Cuvelier, Claude A, van de Loo, Fons, Norris, Paula S, Kruglov, Andrey A, Nedospasov, Sergei A, Rabot, Sylvie, Tito, Raul, Raes, Jeroen, Gaboriau-Routhiau, Valerie, Cerf-Bensussan, Nadine, Van de Wiele, Tom, Eberl, Gérard, Ware, Carl F, Elewaut, Dirk
格式: Artigo
語言:Inglês
出版: BlackWell Publishing Ltd 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331001/
https://ncbi.nlm.nih.gov/pubmed/25599993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489966
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