Chargement en cours...
KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction
Paradoxically, the thymidine kinase (TK) encoded by Kaposi sarcoma-associated herpesvirus (KSHV) is an extremely inefficient nucleoside kinase, when compared to TKs from related herpesviruses. We now show that KSHV-TK, in contrast to HSV1-TK, associates with the actin cytoskeleton and induces extens...
Enregistré dans:
| Publié dans: | EMBO J |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BlackWell Publishing Ltd
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4331000/ https://ncbi.nlm.nih.gov/pubmed/25471072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490358 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|