Advanced Glycation End Products Induce Endothelial-to-Mesenchymal Transition via Downregulating Sirt 1 and Upregulating TGF-β in Human Endothelial Cells

In the present study, we examined the advanced glycation end products- (AGEs-) induced endothelial-to-mesenchymal transition (EndMT) in human umbilical vein endothelial cells (HUVECs). Results demonstrated that AGE-BSAs significantly reduced the cluster of differentiation 31 (CD 31) expression, wher...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: He, Wei, Zhang, Jian, Gan, Tian-yi, Xu, Guo-jun, Tang, Bao-peng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330956/
https://ncbi.nlm.nih.gov/pubmed/25710021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/684242
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