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Heterogeneity for IGF-II production maintained by public goods dynamics in neuroendocrine pancreatic cancer
The extensive intratumor heterogeneity revealed by sequencing cancer genomes is an essential determinant of tumor progression, diagnosis, and treatment. What maintains heterogeneity remains an open question because competition within a tumor leads to a strong selection for the fittest subclone. Canc...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4330744/ https://ncbi.nlm.nih.gov/pubmed/25624490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414653112 |
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