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Deficiency of the Arabidopsis Helicase RTEL1 Triggers a SOG1-Dependent Replication Checkpoint in Response to DNA Cross-Links

To maintain genome integrity, DNA replication is executed and regulated by a complex molecular network of numerous proteins, including helicases and cell cycle checkpoint regulators. Through a systematic screening for putative replication mutants, we identified an Arabidopsis thaliana homolog of hum...

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Bibliographische Detailangaben
Veröffentlicht in:Plant Cell
Hauptverfasser: Hu, Zhubing, Cools, Toon, Kalhorzadeh, Pooneh, Heyman, Jefri, De Veylder, Lieven
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Plant Biologists 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330584/
https://ncbi.nlm.nih.gov/pubmed/25595823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1105/tpc.114.134312
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