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Expression of the 5-HT1A Serotonin Receptor in the Hippocampus Is Required for Social Stress Resilience and the Antidepressant-Like Effects Induced by the Nicotinic Partial Agonist Cytisine

Nicotinic acetylcholine receptor (nAChR) blockers potentiate the effects of selective serotonin reuptake inhibitors (SSRIs) in some treatment-resistant patients; however, it is not known whether these effects are independent, or whether the two neurotransmitter systems act synergistically. We first...

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Publicado en:Neuropsychopharmacology
Main Authors: Mineur, Yann S, Einstein, Emily B, Bentham, Matthew P, Wigestrand, Mattis B, Blakeman, Sam, Newbold, Sylvia A, Picciotto, Marina R
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330507/
https://ncbi.nlm.nih.gov/pubmed/25288485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.269
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