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Blocking Immunosuppressive Checkpoints for Glioma Therapy: The More the Merrier!

Immunosuppressive checkpoints mediated by IDO, CTLA4, and PD1/PDL1 play a critical role in glioma progression and the efficacy of immunotherapies. Combined blockade of these immunosuppressive checkpoints in a glioma model elicited long-term survival. This combined blockade adds to the armamentarium...

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Bibliografiska uppgifter
I publikationen:Clin Cancer Res
Huvudupphovsmän: Castro, Maria G., Baker, Gregory J., Lowenstein, Pedro R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330468/
https://ncbi.nlm.nih.gov/pubmed/24879798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0820
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