Enhancer modeling uncovers transcriptional signatures of individual cardiac cell states in Drosophila

Here we used discriminative training methods to uncover the chromatin, transcription factor (TF) binding and sequence features of enhancers underlying gene expression in individual cardiac cells. We used machine learning with TF motifs and ChIP data for a core set of cardiogenic TFs and histone modi...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Busser, Brian W., Haimovich, Julian, Huang, Di, Ovcharenko, Ivan, Michelson, Alan M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Genomics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330375/
https://ncbi.nlm.nih.gov/pubmed/25609699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv011
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